markers before the trial. The study was selected for women who showed some sort of robust natural immunity that kept them from expressing the HPV markers. 859 were excluded from the final data analysis for technical reasons and the vast majority were found to be infected with HPV-16 before getting the vaccine.
What Exactly Is Cervical Cancer? Cancer begins in cells, the building blocks of tissue which make up the organs. Normally, cells grow and divide to form new cells as the body needs them. When cells grow old, they die and are replaced with new cells. The problem comes in when abnormal cells “appear” and start [...]
To date, GlaxoSmithKline’s HPV-vaccine, Cervarix has been approved in 95 countries around the world, including the 27 member states of the European Union (EU), Australia, Brazil, South Korea, Mexico and Taiwan. Licensing applications have been submitted in more than 20 additional countries including Japan and the United States. GSK also submitted the vaccine to the World Health Organization (WHO) for prequalification in September 2007.
Touting competing studies, Merck and Glaxo use 25th International Papillomavirus Conference as venue to fight for increased sales for their HPV-vaccines, Gardasil and Cervarix. Glaxo released a new Cervarix vs. Gardasil head-to-head study, saying Cervarix prompted a stronger immune response. Merck has been promoting its own ‘new’ study data, which claims Gardasil offers protection from certain HPV strains for up to 9.5 years. Can trial data make a big difference in revenues for either company? Merck is facing declining sales and Glaxo has yet to gain FDA approval and is dealing with efficacy issues in the U.K.
Merck Press release: Studies of GARDASIL, Merck’s Cervical Cancer Vaccine, and HPV 16 Vaccine Component of GARDASIL Presented at International Papillomavirus Conference
Cervical cancer is a major global public health problem affecting socioeconomically deprived populations. It is the most
common cancer among women in low-resource countries where 85% of the global cervical cancer burden of
approximately 493 000 cases and 273 000 deaths are found annually. Recognising the need for a more practical and effective approach to screening and early detection of cervical cancer in
developing countries, Dr Rengaswamy Sankaranarayanan, Head of the Screening Group at IARC, with Dr Bhagwan
Nene and colleagues from the Nargis Dutt Memorial Cancer Hospital (NDMCH), Barshi, India and Dr Surendra Shastri
and colleagues from the Tata Memorial Centre (TMC), Mumbai, India undertook a large randomised controlled trial in the remote district of Osmanabad in Maharashtra State, India.
Dr. David Walmer, a reproductive endocrinologist at Duke University, develops CerviScope, a Cervical Cancer diagnostic tool that is the ultimate in MacGyver-esque resourcefulness. Using parts poached from common, inexpensive items — cheap binoculars, dime-store reading glasses, the plastic innards of a hard hat — Warner and a team of engineers are building a scope that doctors in low-income countries can use to detect cervical cancer.
New information links the Gardasil vaccine to thousand of health complaints and more than 30 deaths. The following video, that warns parents about the dangerous side effects from Gardasil shot, was produced by Jenny Thompson the Director of the Health Sciences Institute.
April 24, 2009 – 12:48 pm
Understanding The Basics Earlier this week I read a report concerning the public’s general confusion about cervical cancer — its causes, detection and treatment. The sentence that I just can’t get out of my mind is a question asked by a teenage boy. “Can I get Cervical Cancer?” The kid was serious and his attitude [...]
The Pap test is recommended for all women, and can be done in a doctor’s office or clinic. During the Pap test, the doctor will use a plastic or metal instrument, called a speculum, to widen your vagina. This helps the doctor examine the vagina and the cervix, and collect a few cells and mucus from the cervix and the area around it. The cells are then placed on a slide or in a bottle of liquid and sent to a laboratory. The laboratory will check to be sure that the cells are normal.